Other labelled uses of acephate are proposed for continued registration with mitigation measures to protect human health and/or the environment. Directions include risk reduction measures to protect human and environmental health. Registered pesticide product labels include specific directions for use. Acephate is an insecticide registered to control a broad spectrum of insect pests on a wide variety of crops and use sites, including forest and woodlots, terrestrial food and feed crops, and outdoor ornamentals. Most uses of acephate have value in the food and non-food agriculture industry and are not of concern to human health or the environment when used according to revised label directions. Acephate -- 97.4% Orthene 97 WP Turf Tree Ornamental - 1can (.773LB) is the proven choice for key insect control in dozens of high value vegetable crops as well as soybeans, cotton and tobacco. The pellet formulation has since been registered for use on tobacco only. It should be noted that only information related to the updated environmental risk assessment or its impact on the value of uses will be considered within the context of this consultation. The registration of certain uses of insecticide acephate in Canada is proposed for cancellation. These types of applications are currently registered for use on various trees and ornamentals, and in Christmas tree plantations, farm woodlots, nurseries, shelter belts, right of ways and municipal parks. on roses and greenhouse ornamentals). In the environment, acephate is metabolized to or degrades to methamidophos. For foliar applications to trees and ornamentals in residential areas, quantitative estimates of exposure and risk were determined for both acephate and methimidophos based on the available data, or using standard defaults in the absence of data. MRLs are specified for acephate and methamidophos on a wide range of commodities. As a result, a risk assessment for the pellet formulation was also conducted for all foliar, soil injection and some tree injection application scenarios currently registered on the label of the soluble powder product. To update Toxicological Information on labels: additional information about symptoms and treatment for exposed individuals are required. Acephate is registered for application to a wide variety of trees using several application methods. Acephate 97UP is water soluble and provides systemic control of insects through root uptake. Re-evaluation draws on data from registrants, published scientific reports, information from other regulatory agencies and any other relevant information available. “Consultation statement” as required by subsection 28(2) of the Pest Control Products Act. Insects eat the foliage of the plants and die. Since Acephate is an Organophosphate insecticide, the chemical works by blocking an enzyme in the nervous system, thus interrupting the essential processes that help the insect communicate with muscles and with other nerves. Health Canada applies internationally accepted risk assessment methods as well as current risk management approaches and policies. Thus, dietary exposure and risk assessments were conducted for both acephate and methamidophos. In addition, for some uses of acephate, there are limited alternative active ingredients, or few other pest management options for the purpose of managing insecticide resistance. Before making a final re-evaluation decision on acephate, the PMRA will consider any comments received from the public in response to Proposed Re-evaluation Decision PRVD2016-01, Acephate. Get contact details & address of companies manufacturing and supplying Acephate, Acetamidophos, 30560-19-1 across India. What Does Health Canada Consider When Making a Re-evaluation Decision? If you would like to comment, please request the full consultation document. Acephate and its major transformation product, methamidophos, break down quickly in soil and water and are not expected to persist in the environment. It is used on food crops, citrus trees, as a seed treatment, on golf courses, and in commercial or institutional facilities. This document (PRVD2019-04) is subject to a 90-day public consultation period, during which the public including the pesticide manufacturers and stakeholders may submit written comments and additional information to the PMRA Publications Section. Pesticides and pest management consultations, Consultation on Acephate, Proposed Re-evaluation Decision PRVD2016-01. When used according to the revised label directions, acephate does not pose an unacceptable risk to the environment. It is used primarily for control of aphids, including resistant species, in vegetables (e.g. Several MRL changes for acephate and methamidophos are proposed as a result of this re-evaluation, as indicated in Section 9.1.1.3 of PRVD2016-01. The Act also requires that products have value when used according to the label directions. These directions must be followed by law. An evaluation of available scientific information found that, under the proposed conditions of use: Health Canada’s pesticide re-evaluation program considers potential risks as well as the value of pesticide products to ensure they meet modern standards established to protect human health and the environment. INTRODUCTION: Acephate is an organophosphate foliar spray insecticide of moderate persistence with residual systemic activity of about 10-15 days at the recommended use rate. It is also used to control ants, wasps, cockroaches, earwigs and other insects in and around residences, institutions, and … This proposal affects all end-use products containing acephate registered in Canada. It also can be applied as a separate treatment using enough water to give adequate coverage of the seed. The aggregate risk index (ARI) based on initial water modelled concentrations was greater than 2 in all populations subgroups except infants, where the ARI was 0.9. As a requirement of the continued registration for these uses, new risk-reduction measures are proposed to be included on the labels of certain products. Frequently, few alternative active ingredients are registered in Canada to control these pests. With refined modelled drinking water concentrations, the estimated chronic exposure ranged from 1-3% of the ADI for acephate and 1-2% of the ADI for methamidophos for the various population subgroups. A pellet formulation was determined to be an acceptable alternative to the soluble powder formulation for most uses, which would require registration for the pellet formulation. Based on the precautions and directions for use on the current product labels, some postapplication risks to workers performing activities such as thinning, pruning and harvesting of crops, did not meet current standards and are of concern. The current consultation covers only revisions to the proposed re-evaluation decision presented in PRVD2019-04. IDENTIFICATION OF THE SUBSTANCE Product Name ACEPHATE 750 SP Insecticide Common Name Acephate Active Ingredient: Acephate (BSI, E-ISO, ANSI, ESA, BPC), (m)(F-ISO, JMAF) Chemical Name: O,S-dimethyl acetylphosphoramidothioate (IUPAC) CAS N o.: 30560-19-1 In the absence of data to estimate risk, a label direction specifying “Not for use with fogging equipment” is required. Directions include risk mitigation measures to protect human health and the environment that must be followed by law. By direct application t… The generation of additional data may refine the current risk assessment and may potentially reduce the proposed REIs. The active ingredient in ACEPHATE 75 SP is acephate, a water soluble insecticide readily absorbed by plant roots and foliage to give systemic control of feeding insects. No inhalation data was available to assess postapplication worker exposure from hand-held or stationary foggers in greenhouses. Each Dendrex unit contains 1.5 grams of acephate insecticide. Acephate is applied using conventional ground application equipment, soil injection, tree trunk injection and implant cartridges by farmers, farm workers and professional applicators. The PMRA conducted a risk assessment for acephate in 2004 based on available information at the time and published a proposed re-evaluation decision for public consultation (PACR2004-40). Pest Management Regulatory Agency What is the proposed Re-evaluation Decision? ACEPHATE 75 SP is an insecticide for control of pests on selected agricultural crops and in certain non-crop areas. Currently, the main product available for foliar applications in various agricultural and horticultural scenarios is packaged as a soluble powder. Residues in drinking water were based on modelling data. Some naturally occurring insect biotypes resistant to TITAN Acephate 970 SG Insecticide and other Group 1B insecticides may exist through normal genetic variability in any insect population. Under controlled laboratory conditions, acephate and methamidophos can be toxic to some nontarget species such as bees, beneficial insects, birds, wild mammals, aquatic invertebrates, amphibians and fish. It also proposes additional risk-reduction measures to further protect human health and the environment. Health Canada applies internationally accepted risk assessment methods as well as current risk management approaches and policies. Other labelled uses of acephate are proposed for continued registration with mitigation measures to protect human health and/or the environment. Acephate contributes to pest management in the ornamental industry. Subsequently, the technical registrants of methamidophos voluntarily discontinued all methamidophos products and the registrations expired in 2012. It can also be applied outdoors in residential areas and is often used to control fire ants. Stakeholder feedback is therefore critical in determining whether these pests are expected to be controlled under the proposed restrictions. Risk mitigation is required for this use. The transformation product methamidophos was included in the risk assessment as it can be more toxic to nontarget organisms than acephate. the levels at which no health effects occur and. At the time that the re-evaluation decision is made, the PMRA will publish an Evaluation Report on acephate in the context of this re-evalulation decision (based on the Science Evaluation of Proposed Re-evaluation Decision PRVD2016-01, Acephate). 610-491-2800 There are limited viable alternative active ingredients to acephate available for the control of tarnished plant bug on celery and pepper maggot on peppers. Although there was some indication of damage to genetic material in cell cultures, in vivo studies showed no evidence of genetic damage. Acephate is an insecticide registered to control a broad spectrum of insect pests on a wide variety of crops and use sites, including forest and woodlots, terrestrial food and feed crops, and outdoor ornamentals. Target MOEs were achieved only when using extensive mitigation such as full personal protective equipment (PPE), engineering controls, lowered rates or removal of specific uses. What Additional Scientific Information is Being Requested? The developing fetus and the juvenile animal did not appear to be more sensitive than the adult animal to the effects of acephate. 4.5 out of 5 stars 10. Acephate 97UP is an insecticide for control of pests on selected agricultural crops and in certain non-crop areas. The PMRA will then publish a Re-evaluation Decision that will include the decision, the reasons for it, a summary of comments received on the proposed decision and the PMRA’s response to these comments. All comments received during the 90-day public consultation period will be taken into consideration in preparation of a re-evaluation decision document,Footnote 2 which could result in revised risk mitigation measures. Acephate, and its major transformation product methamidophos, enter the environment when acephate is used to control insect pests on a wide variety of sites, including forests and woodlots, terrestrial food and feed crops, and outdoor ornamentals. Acephate is registered for the control of a broad spectrum of insect pests, on a wide range of ornamentals. Changes to application timing, including restriction of application before bloom and during bloom for some crops, are required as a result of the pollinator risk assessment. Acephate O,S-Dimethyl acetylphosphoramidothioate . Catalogue number: H113-27/2019-4E-PDF (PDF version). For outdoor and perimeter spray excluding residental turf with Acephate 97UP Insecticide the rate is 1. Active Ingredients: Acephate 98% Additionally, cartridge implants provide protection to trees for a period of 10 to 12 weeks for heavy infestations and up to 18 weeks for light infestations, replacing the need for several foliar applications. The PMRA will assess the combined risks of organophosphate pesticides once all individual organophosphates have been re-evaluated. Once all organophosphate pesticides have been re-evaluated, a cumulative risk assessment will be conducted that will consider potential exposure to all chemicals causing toxicity in the same manner. Estimates of exposure did not reach the target margin of exposure (MOE) or aggregate risk index (ARI) for adults and children for all postapplication scenarios and are, therefore, of concern. It does only list wasps, ants, crickets, earwigs, and pillbugs on the product label for this application, so it would not be the best product … Proposed Re-evaluation Decision PRVD2016-01, Acephate is a consultation document that summarizes the science evaluation for acephate and presents the reasons for the proposed re-evaluation decision. Consideration of and responses to comments pertaining to the health assessment already received for PRVD2016-01 will be presented in the final re-evaluation decision for acephate. Since the 2007 interim mitigation measures for acephate, the PMRA has updated the risk assessments considering new data, inclusion of methamidophos in the risk assessments, and the pellet formulation as a potential replacement of the soluble powder formulation. Agricultural communities apply it to crops such as citrus trees, fruit, potatoes, sugar beets, vine plants, mint, cotton, tobacco, hop cultivation, cranberries, and other berries. Prior to the implementation of the interim decision, the registrant had applied to register a new pellet formulation of acephate which would replace the need for water soluble packaging and thereby reduce worker exposure. This is of particular value to producers of ornamental crops as they typically grow a wide variety of plants which require protection from pests that are often uncommon or sporadic in nature. The re-evaluation considers data and information from pesticide manufacturers, published scientific reports, and other regulatory agencies. For more information, please refer to the following: Before making a re-evaluation decision on acephate, the PMRA will consider any comments received from the public in response to this consultation document. 610-491-2800 Acephate 97UP (1 Pound) -Same ingredient as Orthene 97. You will not receive a reply. “Decision statement” as required by subsection 28(5) of the Pest Control Products Act. Only uses for which the exposure is well below levels that cause no effects in animal testing are considered acceptable for registration. Based on initial modelled drinking water concentrations, the estimated chronic exposure ranged from 8-36% of the acceptable daily intake (ADI) for acephate and 16-69% of the ADI for methamidophos for the various population subgroups. When assessing health risks, two key factors are considered: The dose levels used to assess risks are established to protect the most sensitive human population (for example, children and nursing mothers). In addition, the test data on which the decision is based will also be available for public inspection, upon application, in the PMRA’s Reading Room (located in Ottawa). Use on potatoes is proposed for cancellation. With implementation of proposed mitigation measures, the risk to the environment is expected to be acceptable when acephate is applied as a foliar spray by ground boom to other sites listed on the label. The resistant individuals can eventually dominate the insect population if … For tree implant cartridges, exposure and risk were not of concern when used as per label directions, since applicator exposure was minimal. Regulatory Directive DIR2001-03, PMRA Re-evaluation Program, presents the details of the re-evaluation activities and program structure. Acephate Animals given single doses of acephate exhibited effects on the nervous system (decreased cholinesterase activity), while animals given repeat doses of acephate demonstrated effects on the liver. Occupational postapplication risks are not of concern based on revised label directions. Should you require further information please contact the Pest Management Information Service. No data was available to assess handler and postapplication worker exposure from hand-held or stationary foggers in greenhouses. To obtain a full copy of Proposed Re-evaluation Decision PRVD2019-04, Acephate and Its Associated End-use Products please contact our publications office. Proposed protective measures to reduce worker exposure require consultation with user groups to determine their acceptability. To obtain a full copy of Proposed Re-evaluation Decision PRVD2016-01 Acephate please contact our publications office. Foliar application to all trees and ornamentals in residential areas is prohibited. The risk assessment with revised mitigation measures protects against the effects of acephate by ensuring that the level of human exposure is well below the lowest dose at which these effects occurred in animal tests. For enquiries, contact us. Acephate appears as a white solid. the levels to which people may be exposed. Reference doses define levels to which an individual can be exposed over a single day (acute) or lifetime (chronic) and expect no adverse health effects. RESISTANCE WARNING ACEPHATE 750 SP is a group code 1B insecticide. The available studies did not indicate a concern for an effect on the immune system. This cumulative risk assessment will consider potential exposure to all organophosphate pesticides causing toxicity in the same manner. Under the authority of the Pest Control Products Act and based on the evaluation of currently available scientific information, the registration of certain uses of acephate in Canada are proposed for cancellation. King of Prussia, PA 19406. ACEPHATE 750 SP MATERIAL SAFETY DATA SHEET Page 1 of 6 1. Used as a contact and systemic insecticide. When using the pellet formulation with the various application equipment, the calculated MOEs meet the target MOE with minimal mitigation, such as baseline PPE for most crops and a respirator for a few specific uses. Acephate can enter nontarget terrestrial and aquatic habitats through spray drift and can enter aquatic habitats through runoff and leaching. If in eyes, flush with water.See a physician or contact a poison These label directions can be removed if data are submitted to estimate exposure and demonstrate no risks of concern. Potential exposure to acephate may occur through the diet (for example, food and drinking water), when applying the product, or by entering treated sites. The proposed regulatory decision pertaining to human health was presented in PRVD2016-01, which included, among other mitigation measures, a prohibition of foliar application in residential areas, the cancellation of uses on potatoes, and the replacement of the soluble powder formulation with a pellet formulation. With refined modelled drinking water concentrations and in consideration of mitigation measures and refinements as discussed above, the ARI was greater than 20 for infants and all other population subgroups. The PMRA is requesting feedback on the use pattern for these uses. This label direction can be removed if data are submitted to estimate exposure and demonstrate no risks of concern. Pesticides and pest management consultations, Consultation on acephate and its associated end-use products – Updated environmental risk assessment, Proposed Re evaluation Decision PRVD2019-04, Proposed Re-evaluation Decision PRVD2019-04, Acephate and Its Associated End-use Products, Proposed Regulatory Decision for Acephate. Cancellation of airblast and outdoor mistblower applications, which are currently registered for use on various trees and ornamentals, and in Christmas tree plantations, farm woodlots, nurseries, shelter belts, right of ways and municipal parks, Cancellation of the highest foliar application rate (resulting from the cancellation of applications by airblast/mistblower, the only method for which the highest rate is registered), Uses in farm woodlots, shelter belts, rights of way and municipal parks are limited to spot treatments using hand-held equipment only, Precautionary and hazard statements to inform users of the toxicity and potential risk of acephate to pollinators, beneficial arthropods, birds, mammals, and aquatic organisms, Label statements directing users to avoid application during periods of bloom or during the 9-day period before crop bloom for crops that are attractive to pollinators (or for other crops when using managed bees for pollination services), Statements directing users that tree injection applications must be made after the blooming/pollen shedding period, A label statement directing users not to discharge acephate-contaminated effluent from greenhouses into aquatic environments, Precautionary label statements informing users of ways to reduce the potential for runoff. Although the postapplication risk assessment for the horticultural scenarios identified risks of concern based on the current use pattern, the risk estimates include a number of uncertainties. For more details on the information presented in this Summary, please refer to the Science Evaluation of Proposed Re-evaluation Decision PRVD2016-01, Acephate. Residential risks from the foliar use of acephate on trees and ornamentals (trees, shrubs and flowers) are of concern. All products containing acephate registered in Canada are subject to PRVD2019-04. The transfer of uses from the soluble powder product label to the pellet product label is currently in progress. In the absence of data to estimate risk, a label direction specifying “Not for use with fogging equipment” is required. Occupational (mixer/loader/applicator) risks are not of concern when products are used according to revised label directions and/or products are formulated as a pellet and encapsulated tree implant. These methods and policies also consider the nature of the effects observed and the uncertainties present when predicting the impact of pesticides. Treatment to trees and ornamentals using implant cartridges, and various methods of tree trunk injection resulting in no contact with the foliage is expected to result in minimum exposure to residential populations such as children and gardeners. No mitigation is required. Therefore, mitigation measures are required in order to reduce potential exposure of nontarget organisms and reduce environmental risks. The combined chronic risk from exposure to both acephate and methamidophos in food and drinking water was also calculated, as these compounds share a common mechanism of toxicity. The combined acute risk could not be determined for acephate and methamidophos due to constraints in comparing the toxicological databases of both compounds. Use of acephate may avoid repeated applications of non-systemic and contact insecticides. Pesticide MRLs are established through the evaluation of scientific data under the Pest Control Products Act. Risks to birds and small wild mammals were also identified for broadcast foliar spraying in farm woodlots, shelterbelts, right of ways and municipal parks and were not shown to be acceptable. Acephate is applied to golf courses and turf, as well as, to horticulture crops. Consideration of and responses to comments pertaining to the health assessment already received for PRVD 2016-01 will be presented in the final re-evaluation decision for acephate. Occupational postapplication risks are not of concern if proposed protective measures are followed. Acephate did not cause birth defects in animals and adverse reproductive outcomes were only noted following exposure to high levels. Please forward all comments to Publications. As a result of the re-evaluation of acephate, further risk mitigation measures for product labels are being proposed. Fire Ant Killer Best Value Powder! Dendrex is labeled for aphids, scales, sawflies, beetles, and many other common insect pests. Acephate is a systemic insecticide with long lasting residual activity (typically 10 to 21 days), which is absorbed and transported throughout the plant, thereby protecting the whole plant. INSECTICIDE RESISTANCE WARNING For insecticide resistance management, TITAN Acephate 970 SG Insecticide is a Group 1B insecticide. Acephate 90% SP is a soluble powder used as an insecticide for control of pests on selected agricultural crops and in certain non-crop areas. Acephate is an organophosphate insecticide used to control a broad range of insect pests on a wide variety of sites including forests and woodlots (Christmas tree plantations, farm woodlots, tree nurseries, shelter belts, shade trees), right of ways and municipal parks (excluding national & provincial parks), greenhouse ornamentals, terrestrial food and feed crops (Brussels sprouts, cabbage, cauliflower, celery, field crisphead lettuce, seed and sweet corn, bell pepper, potato, field tomato, cranberry, tobacco, Saskatoon berry) and outdoor ornamentals (numerous flowers, shrubs and trees). As a result, this causes a build-up … In the absence of data to estimate risk, label directions specifying “Not for use with hand-held mist blowers” and “Automated mist blowers are permitted” are required. Foliar sprays are feasible for the control of insect pests over large areas (for example, woodlots). With refined modelled drinking water concentrations, the estimated acute exposure ranged from 23-49% of the ARfD for acephate and 33-56% of the ARfD for methamidophos for the various population subgroups. Dietary risks from food and drinking water are not of concern provided that proposed mitigation measures are implemented. 99 ($2.17/Pound) FREE Shipping. Acephate is an important component of pest management programs to manage economically important pests and is used as a rotational insecticide for managing insect resistance. Acephate is considered toxic to bees with an LC 50 of 1.2 μg per bee. Health or environmental risk is considered acceptable if there is reasonable certainty that no harm to human health, future generations or the environment will result from use of or exposure to the product under its conditions or proposed conditions of registration. Registered pesticide product labels include specific instructions for use. There are no alternative active ingredients to acephate registered in Canada to control root maggots, wireworm on tomato; and rose midge on greenhouse grown roses. The PMRA will accept written comments on Proposed Re-evaluation Decision PRVD2016-01, Acephate up to 60 days from the date of publication of PRVD2016-01. The estimated acute exposure ranged from 600-2900% of the acute reference dose (ARfD) for acephate and 1100-5400% of the ARfD for methamidophos for the various population subgroups. Changes to label statements to include precautionary statements for sites with characteristics that may be conducive to runoff and when heavy rain is forecasted are required to reduce the potential for acephate in runoff to adjacent aquatic habitats. Human exposure to acephate and methamidophos was estimated from residues in treated crops and drinking water, including the most highly exposed population subgroups (for example, infants <1 years, children 1-2 years). Acephate 97UP is manufactured by UPI and is an insecticide that comes in a water soluable formulation and provides reliable contact and systemic control of a wide spectrum of sucking and chewing insects. At one time acephate was used commonly in and around homes, but most of those uses are no longer allowed. It should be noted that restricting tree injection applications to post-bloom periods is contrary to current label directions for certain pests. The final re-evaluation decision will be published taking into consideration the comments and information received. Acephate 97UP also acts on contact, but is more effective when insects ingest the insecticide. These methods consider the unique characteristics of sensitive subpopulations in both humans (for example, children) and organisms in the environment (for example, those most sensitive to environmental contaminants). Uses • Acephate is an organophosphate insecticide currently registered for use on a variety of field, fruit, and vegetable crops (e.g., cotton, tobacco, cranberries, mint); in food handling Changes to label statements, including precautionary statements and buffer zones for nontarget aquatic habitats are required as a result of the environmental risk assessment. Generally, dietary exposure from food and water is not of concern if it is less than 100% of the acute reference dose or chronic reference dose (acceptable daily intake). To protect workers entering treated sites: agronomically feasible restricted-entry intervals (REIs) are proposed; those uses with non-agronomically feasible REIs (for example, outdoor cut flowers and greenhouse cut flowers) are proposed for cancellation. In studies of insecticides commonly used in cotton, acephate was shown to be very toxic to adult Microplitis croceipes parasitoids, and caused 100% mortality at the lowest recommended field rates. 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